Mineral oil is an over-the-counter (OTC) laxative used to treat constipation. Mineral oil blocks water absorption in your colon, which softens your stool and makes it easier to have a bowel movement.7
Vitamin D is a fat-soluble vitamin, absorbed in your body with fats and oils from your diet. Mineral oil may keep the vitamin in the intestines, decreasing its ability to be absorbed and used in other areas.7
The severity of the interaction between vitamin D and mineral oil is low, particularly since mineral oil should be used only as needed.
Healthcare providers typically recommend separating your vitamin D dose from the mineral oil by a few hours.7
What Supplements Not To Mix With Vitamin D
Vitamin D does not appear to interact with many supplements. A few supplements may need to be closely monitored if taken with vitamin D:2
- Calcium: At normal doses, taking vitamin D with calcium helps with calcium absorption. However, high doses of vitamin D can lead to high calcium levels in certain people, which can be harmful.
- Magnesium: Vitamin D may increase magnesium absorption in the body because the same protein that moves calcium through the intestines can also pick up and move magnesium.
When To See a Healthcare Provider
Most drug interactions related to vitamin D supplementation lead to decreased absorption and lower levels of the interacting medication.
Some interactions can also lead to hypercalcemia. Symptoms of hypercalcemia include nausea, vomiting, increased thirst, frequent urination, muscle weakness, bone pain, and confusion.8
If taking medications for arrhythmias or other heart conditions, it’s important to monitor for any signs or symptoms of worsening arrhythmias.
Symptoms include a rapid or slow heart rate, a sensation of skipped beats, dizziness, lightheadedness, shortness of breath, chest pain, or sweating.9
If you begin experiencing any of these symptoms, speak with a healthcare provider.
